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Although the brand can cause weight gain for some users and may lead to other few side effects, it has been beneficial for mood disorders, epilepsy and migraine as this medication contains the active ingredient Divalproex.

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It took me a two to three weeks before I saw a big difference when I started on Depakote (I take the generic Divalproex).

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In May 2010, researchers found that could be caused by using the drug as early as the first trimester, which means that by the time many women discover they are pregnant, it could be too late to get off the drug and avoid birth defects for their unborn child.

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In overdose situations, the fraction of drug not bound to protein is high and hemodialysis or tandem hemodialysis plus hemoperfusion may result in significant removal of drug.

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This alert is based on the final results of the Neurodevelopmental Effects of Antiepileptic Drugs (NEAD) study showing that children exposed to valproate products while their mothers were pregnant had decreased IQs at age 6 compared to children exposed to other anti-epileptic drugs (see Data Summary).

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One study has suggested that 80% of women treated with valproic acid before the age of 20 have polycystic ovaries or hyperandrogenism.

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After I got off this drug I lost 160lbs.

However, since valproate may interact with these or other concurrently administered AEDs as well as other drugs (see Drug Interactions), periodic plasma concentration determinations of concomitant AEDs are recommended during the early course of therapy (see PRECAUTIONS - Drug Interactions).

While no Depakote recall has been issued, one Depakote birth defect class action lawsuit was filed in March 2011 in St.

Pregnancy Registry: If you become pregnant while taking Depakote, talk to your healthcare provider about registering with the North American Antiepileptic Drug Pregnancy Registry.

What are the most common side effects of Depakote?

The Udvalg for Kliniske Undersogeiser (UKU) Side Effect Rating Scale will be administered at base line and weekly for the remainder of the study to determine the medication side effect profiles.

If proper warnings had been provided, women who were planning to become pregnant or those not practicing birth control, could have taken a different anti-seizure medication during pregnancy, as not all epilepsy drugs have the same risk of birth defects as Depakote.

Generic divalproex sodium will have the same safety warnings as Depakote, including a Boxed Warning that cautions about the risk of liver damage (hepatotoxicity), including fatalities, and pancreatitis, or an inflamed pancreas, including fatal cases.

It tends to cause fewer GI side effects than Depakene, is absorbed more slowly, and has a somewhat longer half life (12 hours vs.

Through use of co-counsel and local attorneys, cases are reviewed nationwide, but are not accepted in every state.

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At first the medicine did its job, not perfect but at least no serious side affect that i could see.

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Depakote has been marketed in the United States since 1983 as a treatment for simple and complex absence seizures.

If I have a very stressful work day ahead, I take an additional 1 in the morning.

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Odds ratios were also adjusted for the individual registry (registries with no entries for valproic acid exposure were excluded) in the comparison of exposure to valproic acid monotherapy with no exposure to antiepileptic drugs; there were too few controls to make this adjustment in other comparisons.

Two six-month pediatric studies were conducted to evaluate the long-term safety of Depakote ER for the indication of mania (292 patients aged 10 to 17 years).

Topamax soon wasn't enough so my doc tried Latuda and it didn't work.

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Or complete this form to have RLG review your case promptly and contact you to confidentially discuss the process of seeking compensation for medical bills, lost wages, pain and suffering, and other damages.

I've provided will be used only by AbbVie and its contracted third parties to contact me by mail, email, and phone with helpful information on my condition, DEPAKOTE and other AbbVie treatments, products and services.

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It is generally treated with a nutritionally balanced diet and niacin supplements.

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BUT NOTE: it is ONLY FDA approved for bipolar mania, NOT for bipolar depression.

Research indicated that birth defects were discovered in 20 percent of pregnant Depakote users.

USES: Carbamazepine is used to prevent and control seizures.

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Exploiting the fact that certain OBRA provisions did not yet apply to Depakote, Abbott sales representatives stated that by using Depakote, nursing homes could avoid the administrative burdens and costs of complying with OBRA.

He also of course was calling himself names and saying he wished he was dead and he hates me among other things.

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Can cause liver damage, so it's probably not safe if you already have liver problems.

Carbatrol (carbamazepine), and Lamictal (lamotrigine) reduce the effect of Depakote.

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One contributing factor is the nonlinear, concentration dependent protein binding of valproate which affects the clearance of the drug.

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And then there's the corporate integrity agreement, a 5-year pledge that Abbott's board and top executives will get involved in the company's compliance efforts.

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On July 10, 2008, an advisory panel was convened by the Food and Drug Administration (FDA) to review data that the FDA had previously collected from drug studies showing an association between many of the antiepileptic drugs (AEDs) and suicidal ideation and behavior, which together are called suicidality.

Stopping suddenly may cause a serious, life-threatening type of seizure.

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

However, it did not help with mania mood swings.

Signs of a very bad reaction to the drug.

Sold by Abbott Laboratories, the drug comes in a variety of forms: Depacon injections (valproate sodium), Depakote, Depakote CP and Depakote ER (divalproex sodium) and Depakene and Stavzor (valproic acid).

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ANTIEPILEPTIC DRUGS, INCLUDING VALPROATE, SHOULD BE ADMINISTERED TO WOMEN OF CHILDBEARING POTENTIAL ONLY IF THEY ARE CLEARLY SHOWN TO BE ESSENTIAL IN THE MANAGEMENT OF THEIR MEDICAL CONDITION.

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Abbott was named one of the 2014 Top 20 Employers by the journal Science and listed as a Top 10 company for women by Working Mother magazine and the National Association for Female Executives.

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PATIENT WHO HAD LOW FIBRINOGEN WHEN TAKING MULTIPLE ANTICONVULSANTS INCLUDING VALPROATE GAVE BIRTH TO AN INFANT WITH AFIBRINOGENEMIA WHO SUBSEQUENTLY DIED OF HEMORRHAGE.

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Serious skin reactions (such as Stevens-Johnson Syndrome and toxic epidermal necrolysis) have been reported with concomitant lamotrigine and valproate administration.

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Anti-seizure medications: Phenytoin (Dilantin) and valproic acid (Depakote) may cause niacin deficiency in some people.

Before using Depakote ER, a woman who can become pregnant should consider the fact that Depakote ER has been associated with birth defects, in particular, with spina bifida and other defects related to failure of the spinal canal to close normally.

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Advise patient to immediately report signs and symptoms of liver dysfunction (such as malaise, weakness, lethargy, appetite loss, vomiting, or yellowing of skin or eyes), signs and symptoms of pancreatitis (such as abdominal pain, nausea, vomiting, loss of appetite), or suicidal behavior or ideation.

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Nicotine patches: Using nicotine patches with niacin may worsen or increase the risk of flushing associated with niacin.

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FDA and reported my experience, I would hate for anyone to go through that.

Abbott's first international affiliate was in London in 1907, and the company later added an affiliate in Montreal, Canada (Fact 21).

It may also be used for other conditions as determined by your doctor.

If the weight gain continues as it does not seem to be leveling off then not only will she be dealing with self esteem issues for the first time in life related to weight but her weight will become a new health issue itself.

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According to office-based physician survey data for 2012, 57% of all drug use mentions for valproic acid and derivative products in women of reproductive potential age were associated with diagnoses of episodic mood disorders, 10% for the diagnoses of schizophrenic disorders, 9% for migraine, and 9% for epilepsy and recurrent seizures.

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Depakote ER 500 mg for 10 days now, or maybe I should say nights.

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