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Topiramate in the prophylactic treatment of cluster headache".

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This rapid onset of action coupled with its muscle spasmolytic and antinociceptive properties has spurred investigation into clinical use not only for the treatment of acute spinal pain with muscle spasm, but also as therapy for other painful chronic muscular conditions.

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Rational physical, medical, and surgical therapies can be selected by determining the relevant pathoanatomy and causal pain generators.

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The researchers utilized both disease-specific and general instruments to quantify the impact of migraine on daily activities.

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Most of the time, doctors will prescribe the standard dose, although select patients can be prescribed a much higher dose than usual.

An explanation for the association of topiramate capsules (sprinkle) and kidney stones may lie in the fact that topiramate is a carbonic anhydrase inhibitor.

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Fitness may be correlated with the time to recovery and return to work after LBP; however, in prospective studies controlled for age, isometric lifting strength and the degree of cardiovascular fitness were not predictive of back injury.

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During testing, two subjects (one male, one female) reported adverse effects at the 300 mg dose.

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Patients selected for the trial were being treated with traditional AEDs; their average seizure frequency was approximately 11 per month at the time they entered the trial.

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There were no clinically significant changes in the systemic exposure of risperidone plus 9-hydroxyrisperidone or of topiramate; therefore this interaction is not likely to be of clinical significance.

The amount of weight loss appears to be related to some factors such as the duration of the treatment and a high baseline body mass index (BMI), while the role of daily dosage and gender of patients is controversial.

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Clinical effectiveness, tolerability and cost-effectiveness of newer drugs for epilepsy in adults: a systematic review and economic evaluation.

Do not start, stop, or change the dose of any drug without checking with your doctor.

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We again urge patients and families to contact their doctor before stopping an epilepsy medication because this may possibly lead to seizures and worsening of mood.

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Because this is a ministerial listing, comments should be limited to whether FDA requires that topiramate be labeled to communicate a risk of reproductive or developmental harm.

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During the acute phase following biomechanical injury to the spine, where there are no fractures, subluxation, other serious osseous lesions, or significant neurological sequelae, mild narcotic analgesics may assist patients in minimizing inactivity and safely maximizing the increase in activity, including prescribed therapeutic exercises.

Topiramate) adverse reactions causing discontinuation in this trial were difficulty with memory, fatigue, asthenia, insomnia, somnolence, and paresthesia.

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The first level one evidence trial assessed the safety and efficacy of topiramate in migraine prevention.

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The effectiveness of topiramate as an adjunctive treatment for primary generalized tonic-clonic seizures in patients 2 years old and older was established in a multicenter, randomized, double-blind, placebo-controlled trial, (Study YTC), comparing a single dosage of topiramate and placebo (see Table 15).

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